An Evaluation of the Accuracy of Hepatitis B Variables in Birth Records

Tuesday, June 21, 2016: 11:30 AM
Tikahtnu A, Dena'ina Convention Center
Genny Grilli , Minnesota Department of Health, St. Paul, MN
BACKGROUND:  The work of the Perinatal Hepatitis B Prevention Program (PHBPP) includes identifying infants born to HBV-positive women and ensuring they receive appropriate post-exposure prophylaxis (PEP). To assist in this effort, variables related to hepatitis B were added to Minnesota birth records in 2011. These variables include data on administration of hepatitis B vaccine and hepatitis B immune globulin (HBIG) and two variables on maternal HBV status. This evaluation uses Minnesota data to assess the accuracy of HBV variables in birth records data and to identify infants born to HBV-positive women that were missed during routine surveillance.

METHODS:  The data included Minnesota birth records from the 2014 birth cohort and HBV surveillance records from the hepatitis disease surveillance system. Variables related to hepatitis B in the two datasets were compared to identify discrepancies for infants born to known HBV-positive women. To identify potentially missed births and evaluate data validity, infection status was investigated in all women marked as HBV-positive in birth records who had not been reported to the hepatitis surveillance program. LinkPlus record linking software was used to identify known HBV-positive women who gave birth in 2014 in order to identify missed births.

RESULTS:  Of the 439 infants identified as being born to HBV-positive women in 2014, 230 (52%) had accurate data for all four variables related to hepatitis B. The most consistent variable was the birth dose of the hepatitis B vaccine, which was accurately documented in 419 (95%) of records. Only 333 (76%) records had accurate documentation of HBIG administration. For maternal characteristics, the single-select variable for hepatitis B infection status was more likely to be accurate than the variable with HBV status included on a list of maternal infections, 339 (77%) and 313 (71%) respectively.

There were 200 women documented as HBV-positive on birth records with no evidence of current infection in surveillance records. Following investigation, none were found to be currently HBV-positive.

By investigating matched cases and confirming diagnoses with prenatal clinics, we identified 12 infants born to HBV-positive women who were not previously reported to PHBPP.

CONCLUSIONS:  Birth records data can be a valuable tool in identifying infants born to HBV-positive women. However, inconsistencies in the data persist and more work needs to be done to ensure hepatitis B data on birth records is accurate before it can be used to ensure appropriate PEP of at-risk infants and identification of HBV-positive women.