Patterns of Buprenorphine-Naloxone Prescription-Filling Among New York City Residents Initiating Buprenorphine Treatment in 2011

Monday, June 20, 2016: 4:24 PM
Tubughnenq' 3, Dena'ina Convention Center
Ellenie Tuazon , New York City Department of Health and Mental Hygiene, Long Island City, NY
Denise Paone , New York City Department of Health and Mental Hygiene, Long Island City, NY
Hillary Kunins , New York City Department of Health and Mental Hygiene, Long Island City, NY
BACKGROUND:  The use of buprenorphine-naloxone (BUP-N) to treat opioid use disorders is effective, and longer retention in treatment is associated with improved health outcomes. However, population-level retention in buprenorphine care is unknown. This study uses New York State Prescription Monitoring Program (PMP) data to describe characteristics of New York City (NYC) residents who initiate buprenorphine treatment over a three-year period.

METHODS:   We conducted a retrospective analysis of BUP-N prescriptions filled by NYC residents over a three-year period (2011­­–2013) using New York State’s PMP data.  To examine retention in care, we created an inception cohort of all patients newly prescribed BUP-N in 2011 (without a prior-year BUP-N prescription). Patients were described by gender, age, most frequent payment method, and proportion with <3, 3-6, 7-12, and >12 months of consecutive BUP-N prescriptions filled. We also examined median dose at initiation, and in subsequent buprenorphine prescriptions.

RESULTS:  There were 6,119 patients who were newly prescribed buprenorphine-naloxone in 2011. From 2011-2013, this cohort filled 64,458 prescriptions. Patients were 74% male and median age 39 years. The most frequent payment method was commercial insurance (50%), followed by public insurance (31%). The median months filled during the three-year period was 3 (range 1-36). Nearly half (49%) of patients filled <3 months; 22% filled 3-6 months; 14% filled 7-12 months; and 16% filled >12 months.  Median dose at initiation was 16 milligrams. For patients with 2 or more months of buprenorphine prescriptions, the median dose was also 16 milligrams.

CONCLUSIONS:  NYC residents who newly fill buprenorphine-naloxone prescriptions have short durations of consecutive prescriptions, with nearly half for fewer than 3 months. Future research is needed to elucidate why treatment duration is so short. Extending length of time in treatment may help patients avoid adverse health consequences from opioid use disorders.