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BACKGROUND: Mandated All Payer Claims data (APCD) sets the stage for limitless population-based ways to explore reducing risks in the delivery of surgical care associated with potentially controllable pre- and post- hospitalization factors. OBJECTIVE: To determine the epidemiology of prior hospitalization antiplatelet use in patients with traumatic injuries as a foundation for profiling operative and post-operative increased hemorrhage risk difference by gender, age, diagnosis, and discharge disposition.
METHODS: The medical claims and pharmacy claims for 12,896 private insurer beneficiaries in APCD for calendar years 2010 and 2011 who required inpatient hospitalization for primary diagnosis of traumatic injury and who during the same 2-year period obtained prescription drug therapy were evaluated for completeness of drug name data, date prescription filled, and highest medical claim version.
RESULTS: Complete highest version data for 7,767 patients (52% male, mean age male = 47, mean age female = 52) were stratified by maximum date of all prescriptions before and after date of admission for traumatic injury. Gender differences were small in proportion of patients taking any antiplatelet drugs (22.3%, (female 10.9%, male 11.4%)) versus antiplatelet drugs before admission (4.95% (female 10.3%, male 11.8%)), and in the risk of death by gender (RR = 0.96, 95% CI (0.51-1.81). However, before admission antiplatelet users were at increased risk of requiring transfusion products (RR = 0.58, 95% CI (0.41 – 0.72), p < 0.0001) across demographic groups.
CONCLUSIONS: Linked APCD Medical-Pharmacy data can reliably be used to profile ongoing prescription drug use that may impact injury and healing risks.